P4HB anticorps

N° du produit ABIN372745

Cet anticorps Lapin Polyclonal détecte spécifiquement P4HB dans WB, IF et IHC (p). Il présente une réactivité envers Humain, Souris, Rat et Singe.

Aperçu rapide pour P4HB anticorps (ABIN372745)

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P4HB est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-P4HB anticorps

Specificité: Recognizes endogenous levels of total P4HB.

Réactivité croisée (Details): Species reactivity (expected):Monkey, Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide conjugated to KLH derived from the sequence around Proline 329 of Human P4HB.

Isotype: IgG

Information d'application

Indications d'application: Western Blot. Immunofluorescence. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 10 mM Sodium HEPES, pH 7.5, 150 mM Sodium Chloride, 0.1 mg/mL BSA, 50 % Glycerol

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur P4HB

Antigène: P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))

Autre désignation: PDI / P4HB

Sujet: P4HB, Prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds.Synonyms: Cellular thyroid hormone-binding protein, ER marker, ERBA2L, P4HB, PDI, PDIA1, PO4DB, Prolyl 4-hydroxylase subunit beta, Protein Disulfide Isomerase, Protein disulfide-isomerase, p55

Poids moléculaire: 57 kDa.

ID gène: 5034

NCBI Accession: NP_000909

UniProt: P07237

Pathways: Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism